Metformin ameliorates a β pathology by insulin-degrading enzyme in a transgenic mouse model of alzheimer ’ s disease

HIGHLIGHTS

  • who: Xin-Yi Lu and colleagues from the Biological Resource Center, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China have published the research: Metformin Ameliorates A β Pathology by Insulin-Degrading Enzyme in a Transgenic Mouse Model of Alzheimer ’ s Disease, in the Journal: Oxidative Medicine and Cellular Longevity of 21/04/2020
  • what: In this experiment, the authors further investigated the neuroprotective mechanism of metformin on APP/PS1 mice.
  • how: Morris water maze and Y-maze results indicated that metformin could improve the learning and memory ability in APPswe . . .

     

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