Metformin impacts human syncytiotrophoblast mitochondrial function from pregnancies complicated by obesity and gestational diabetes mellitus in a sexually dimorphic manner

HIGHLIGHTS

  • who: Jessica F. Hebert and Leslie Myatt from the Department of Obstetrics and Gynecology, Oregon Health and Science University, Portland, OR, USA have published the Article: Metformin Impacts Human Syncytiotrophoblast Mitochondrial Function from Pregnancies Complicated by Obesity and Gestational Diabetes Mellitus in a Sexually Dimorphic Manner, in the Journal: Antioxidants 2023, 12, 719. of /2023/
  • what: The authors examine how metformin commonly used to treat type A2 GDM affects placental metabolism as well as content and function. The study shows that viable mitochondrial content remained relatively unchanged with metformin treatment.

SUMMARY

     

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