HIGHLIGHTS
- who: Titia E. Woudenberg-Vrenken¤a et al. from the Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands have published the research: Metformin Protects Rat Hepatocytes against Bile Acid- Induced Apoptosis, in the Journal: PLOS ONE | www.plosone.org of August/12,/2013
- what: The authors investigated the hepatoprotective effects of metformin in models of TNFa- and bile acid-induced apoptosis in primary rat hepatocytes. The authors show that metformin is protective against bile acid-induced cell death, while it has no effect on TNFa-induced apoptosis.
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