HIGHLIGHTS
- who: November and colleagues from the University of Tennessee Health Science Center (UTHSC), United States have published the article: Methadone alters the peripheral in ammatory and central immune landscape following prenatal exposure in rats, in the Journal: (JOURNAL)
- what: The authors show shifts in cerebral immune cell populations, defined specifically by increased neutrophils and regulatory T-cells, occurring months after prenatal opioid exposure. The authors demonstrate evidence of peripheral inflammation alongside immune priming and sustained peripheral immune reactivity (SPIHR) following prenatal opioid exposure that extends beyond the neonatal period. Beyond molecular inflammation, this study shows . . .
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