Methylation of the phospholipase a2 receptor 1 promoter region in childhood b cell acute lymphoblastic leukaemia

HIGHLIGHTS

  • who: Receptor and collaborators from the InstitutUniversity Hospital have published the research: Methylation of the Phospholipase A2 Receptor 1 Promoter Region in Childhood B Cell Acute Lymphoblastic Leukaemia, in the Journal: Scientific Reports Scientific Reports of May/23,/2013
  • what: In the present study, patients were subdivided into groups with standard, medium, and high risk according to the AIEOP-BFM ALL 2009 guidelines and the PLA2R1 promoter methylation on day 15 of the ALL induction treatment was evaluated as biomarker for risk stratification (Fig 4). The data of this study demonstrated that PLA2R1 promoter methylation . . .

     

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