Methylphenidate analogues as a new class of potential disease-modifying agents for parkinson’s disease: evidence from cell models and alpha-synuclein transgenic mice

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  • who: Andrea Casiraghi et al. from the Department of Pharmaceutical Sciences, University of Milan, Via Luigi Mangiagalli, Milano, Italy have published the paper: Methylphenidate Analogues as a New Class of Potential Disease-Modifying Agents for Parkinson’s Disease: Evidence from Cell Models and Alpha-Synuclein Transgenic Mice, in the Journal: Pharmaceutics 2022, 14, 1595. of 22/09/2010
  • what: The results presented above support that among the selected MPH derivatives, compound I-threo exhibited an improved ability to stimulate the functional αSyn/Syn III interaction.
  • how: All the experiments were conducted during daylight . . .

     

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