Mettl3-dependent m6a modification attenuates the brain stress response in drosophila

HIGHLIGHTS

  • who: Alexandra E. Perlegos from the (UNIVERSITY) have published the research work: Mettl3-dependent m6A modification attenuates the brain stress response in Drosophila, in the Journal: (JOURNAL) of 16/07/2021
  • what: The authors investigate the impact of m6A mRNA methylation in the adult Drosophila brain with stress. Through m6A-immunoprecipitation sequencing, the authors show 5u2032UTR Mettl3-dependent m6A is enriched in transcripts of neuronal processes and signaling pathways that increase upon stress. To investigate this response further, the authors focused on the 30 min HS timepoint, as it showed the most significant increase in . . .

     

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