Mgmt gene promoter methylation by pyrosequencing method correlates volumetric response and neurological status in idh wild-type glioblastomas

HIGHLIGHTS

  • who: Tomohiro Hosoya from the Department of Neurosurgery and Neurou2011Oncology, National Cancer Center Hospital, u20111u20111, Tsukiji, Chuou2011ku, Tokyo, u20110045, Japan have published the research work: MGMT gene promoter methylation by pyrosequencing method correlates volumetric response and neurological status in IDH wild-type glioblastomas, in the Journal: (JOURNAL)
  • what: The aim of this study was to determine the optimal cutoff value of MGMT promoter methylation status using volumetric analysis focused on the tumor volume ratio (TVR) measured by MRI. In this study, to obtain more specific and useful information about the response to temozolomide and the . . .

     

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