Micro-abnormalities in the retina and choroid induced by anti-ctla4 treatment

HIGHLIGHTS

• who: Ryo Mukai from the DepartmentGunma University have published the Article: Micro-abnormalities in the retina and choroid induced by anti-CTLA4 treatment, in the Journal: Scientific Reports Scientific Reports
• what: The authors investigated whether anti-CTLA4 agent, induces retinal and choroidal impairments in rodents.

SUMMARY

Briefly, animals were intraperitoneally injected with 300 μg/100 μL of anti-CTLA4 antibody (Bio X Cell, Lebanon, NH, USA; InvivoMab 9D9; Cat. #BE0164), which was adjusted with phosphate-buffered saline (PBS), three times weekly (days 0, 1, and 3) for 5 weeks. The PNA . . .

 



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