Microbial solvent formation revisited by comparative genome analysis

HIGHLIGHTS

  • who: Anja Poehlein from the 900s, due to their potential for the commercial production of solventsInitial studies were centered on production of butanol for the manufacture of synthetic rubber. With the advent of WW1, emphasis rapidly shifted to the production of acetone that was needed in large volumes for the production of munitions. In, Charles (later Chaim) Weizmann from the University of Manchester was granted his famous patent for the production of acetone and butanol using an anaerobic bacterium [2]. This organism was later named Clostridium acetobutylicum [3]. During WW1, the production of acetone on industrial scale . . .

     

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