Microbial sophorolipids inhibit colorectal tumour cell growth in vitro and restore haematocrit in apc

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  • who: Breedge Callaghan from the School of Biomedical Sciences, Ulster University, Coleraine , SA, UK have published the article: Microbial sophorolipids inhibit colorectal tumour cell growth in vitro and restore haematocrit in Apc, in the Journal: (JOURNAL)
  • what: The authors investigated the targeted therapeutic effect of purified ASL in_vitro in human colorectal cancer cell lines and their ability to inhibit tumour growth in u00adApcmin+/-mice. The study demonstrated that a preparation dominated by a single congener of ASL at low concentrations (40 u00b5g u00admL-1) induced cell rounding, cytoplasmic condensation and cell detachment in all the . . .

     

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