Microevolution of candida albicans in macrophages restores filamentation in a nonfilamentous mutant

HIGHLIGHTS

• who: Anja Wartenberg and collaborators from the Germany, Septomics Research Center, Friedrich Schiller University and Leibniz Institute for Natural Product Research and Infection Biology, Hans Knoell Institute, Jena have published the paper: Microevolution of Candida albicans in Macrophages Restores Filamentation in a Nonfilamentous Mutant, in the Journal: (JOURNAL) of October/15,/2014
• what: The authors show that adaptation to macrophages leads to distinct phenotypic differences between the pre- and post-passaged strains with regained filamentation in the latter. As the SNP at nucleotide position 1,055 in the SSN3 ORF (Fig 6A) was detected in . . .
  

   

  

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