HIGHLIGHTS
- who: Qian Bai and colleagues from the Department of Ophthalmology, Xijing Hospital, Fourth Military Medical University, Xi`an, China have published the Article: Microglia-Derived Spp1 Promotes Pathological Retinal Neovascularization via Activating Endothelial Kit/Akt/mTOR Signaling, in the Journal: (JOURNAL) of 11/01/2023
- what: Of this study showed that: (a) Spp1 was mainly secreted from active microglia in pathological RNV; (b) expression of Spp1 was regulated by HIF-1 signaling pathway and NF-u03baB signaling pathway; (c) microglia-derived Spp1 enhanced EC proliferation and migration via activating Kit/Akt/mTOR signaling cascade; and_ . . .
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