Microglia modulate proliferation, neurite generation and differentiation of human neural progenitor cells

HIGHLIGHTS

  • who: TYPE and collaborators from the University of Milan, Italy have published the article: Microglia modulate proliferation, neurite generation and differentiation of human neural progenitor cells, in the Journal: (JOURNAL)
  • what: The authors investigated the modulatory effect of microglial cells on the polarization and differentiation of human stem_cell-derived NPCs. The neural progenitor cell lines used in this study have previously been generated and characterized in detail (Yu et_al, 2014; Vofely et_al, 2018; Lilienberg et_al, 2021).
  • how: Similar results were obtained with co-cultures to that seen with the BV2 supernatants nau00efve microglia . . .

     

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