Microglia-specific deletion of histone deacetylase 3 promotes inflammation resolution, white matter integrity, and functional recovery in a mouse model of traumatic brain injury

HIGHLIGHTS

  • who: Yongfang Zhao from the Pittsburgh Institute of Brain Disorders and Recovery and Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA have published the article: Microglia-specific deletion of histone deacetylase 3 promotes inflammation resolution, white matter integrity, and functional recovery in a mouse model of traumatic brain injury, in the Journal: (JOURNAL)
  • what: This study aimed to investigate the role of HDAC3 in microglial responses after TBI, and utilized this novel conditional HDAC3 knockout mouse model to specifically ablate HDAC3 in microglia. Detailed information on the animals used in this study and timepoints . . .

     

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