Microglia specific deletion of mir-155 in alzheimer’s disease mouse models reduces amyloid-β pathology but causes hyperexcitability and seizures

HIGHLIGHTS

• who: Macarena S. Aloi from the Department of Laboratory Medicine and Pathology, School of Medicine, University of Washington, Seattle, WA, USA have published the paper: Microglia specific deletion of miR-155 in Alzheimeru2019s disease mouse models reduces amyloid-u03b2 pathology but causes hyperexcitability and seizures, in the Journal: (JOURNAL)
• what: Since a single miRNA can modulate expression of many effector genes, the authors focused on identifying changes in expression of genes that are confirmed or interesting putative targets for miR-155. The authors focused on changes in expression of miR-155 target genes: cMaf (cMAF . . .
  

   

  

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