Microglia subtypes show substrate- and time-dependent phagocytosis preferences and phenotype plasticity

HIGHLIGHTS

  • who: Shuailong Li from the Complutense University of Madrid, Spain have published the research: Microglia subtypes show substrate- and time-dependent phagocytosis preferences and phenotype plasticity, in the Journal: (JOURNAL)
  • what: This study examined phagocytosis efficiencies of M0-, M1-, and M2-like microglia for E.coli particles and IgG-opsonized beads over different time periods in_vitro.
  • how: Together these results indicated that M1- and M2-like microglia subtypes show substrate-specific phagocytosis activities. microglia morphology between microglia revealed a smaller cell size of M1- than M2-like microglia and a higher circularity of . . .

     

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