Microglial activation, tau pathology, and neurodegeneration biomarkers predict longitudinal cognitive decline in alzheimer`s disease continuum

HIGHLIGHTS

  • who: Qing-Qing Tao from the Geneva University Hospitals (HUG), Switzerland have published the research work: Microglial Activation, Tau Pathology, and Neurodegeneration Biomarkers Predict Longitudinal Cognitive Decline in Alzheimer`s Disease Continuum, in the Journal: (JOURNAL)
  • what: The authors aimed to determine these three aspects of biomarkers in cerebrospinal fluid (CSF) and plasma to cognition status using Alzheimer`s Disease Neuroimaging (ADNI) cohort. CSF sTREM2 CSF and plasma p-tau181 had similar medium prediction effects while brain volumes showed stronger effects in predicting cognition Frontiers in Neuroscience | www.frontiersin.org June 2022 | Volume 14 | Article . . .

     

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