Microglial inflammatory-metabolic pathways and their potential therapeutic implication in major depressive disorder

HIGHLIGHTS

  • who: Naguib Mechawar from the uglas Mental Health University Institute, McGill Group for Suicide, Verdun, QC, Canada, Integrated Program have published the Article: Microglial Inflammatory-Metabolic Pathways and Their Potential Therapeutic Implication in Major Depressive Disorder, in the Journal: (JOURNAL)
  • what: In the following sections, the authors aim to highlight the potential roles played by microglia in the pathogenesis of MDD, with a focus on the roles played by the canonical pro-inflammatory, anti-inflammatory and metabolic pathways.
  • how: These results indicated that TNF-u03b1 regulation of striatal morphology was predominated by TNFR1 . . .

     

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