Microrna-223 suppresses human hepatic stellate cell activation partly via regulating the actin cytoskeleton and alleviates fibrosis in organoid models of liver injury

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  • who: Chaiyaboot Ariyachet et al. from the Department of Biochemistry, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand have published the article: MicroRNA-223 Suppresses Human Hepatic Stellate Cell Activation Partly via Regulating the Actin Cytoskeleton and Alleviates Fibrosis in Organoid Models of Liver Injury, in the Journal: (JOURNAL)
  • what: The authors investigated the roles of miR-223 in HSC activation in primary human HSCs, the gold standard to study human liver fibrosis in_vitro, and its therapeutic potential in controlling fibrosis using injury models of co-cultured human hepatic organoids. The authors aimed to study fibrotic . . .

     

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