Microsomal prostaglandin e synthase-1 gene deletion impairs neuro-immune circuitry of the cholinergic anti-inflammatory pathway in endotoxaemic mouse spleen

HIGHLIGHTS

  • who: Priya Revathikumar and colleagues from the Rheumatology Unit, Department of Medicine, Solna, Karolinska Institutet, Karolinska University Hospital have published the article: Microsomal prostaglandin E synthase-1 gene deletion impairs neuro-immune circuitry of the cholinergic anti-inflammatory pathway in endotoxaemic mouse spleen, in the Journal: PLOS ONE | https://doi.org/10.1371/journal.pone [0193210]. February 22, 2018 of December/11,/2017
  • what: The authors aimed to dissect the role of mPGES-1 dependent PGE2 synthesis in the neuro-immune circuitry of the CAP during endotoxaemia in mice. This study was performed according to . . .

     

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