HIGHLIGHTS
- who: Mid et al. from the of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL have published the article: Mid51/Fis1 mitochondrial oligomerization complex drives lysosomal untethering and network dynamics, in the Journal: (JOURNAL) of 26/02/2023
- what: Using super-resolution and live microscopy, the authors demonstrate here that dynamic inter-lysosomal tethers frequently form to modulate lysosomal networks and are distinct from lysosomal fusion events. The authors show that Fis1 oligomers directly promote the oligomerization of the mitochondrial adaptor Mid51, which is important for driving Drp1 oligomerization on mitochondria required for subsequent . . .
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