Mif homolog d-dopachrome tautomerase (d-dt/mif-2) does not inhibit accumulation and toxicity of misfolded sod1

HIGHLIGHTS

  • who: Amina Alaskarov from the DepartmentGurion University have published the Article: MIF homolog d-dopachrome tautomerase (D-DT/MIF-2) does not inhibit accumulation and toxicity of misfolded SOD1, in the Journal: Scientific Reports Scientific Reports of 27/05/2022
  • what: The authors report that overexpressing D-DT in neuronal cells did not reduce misfolded SOD1 accumulation as detected with the B8H10 antibody (Fig 3B-C). The authors investigated D-dopachrome tautomerase (D-DT or MIF-2), a second member of the MIF protein superfamily and known homolog to MIF, encoded by the DDT u00adgene45 . . .

     

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