Miip downregulates pd-l1 expression through hdac6 in cutaneous melanoma

HIGHLIGHTS

  • What: The authors verified that melanoma patients exhibited a negative MIIP expression and predicted worse overall survival when compared with patients with a positive MIIP expression.
  • Who: Ting Li from the Methods A cohort of , patients with histologically confirmed melanoma from Tianjin Medical University Cancer have published the article: MIIP downregulates PD-L1 expression through HDAC6 in cutaneous melanoma, in the Journal: (JOURNAL)
  • How: To ensure that off-target effect was not affecting the analysis the authors used two different siRNAs to target MIIP for side-by-side experiments. The results showed that . . .

     

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