Milk disrupts p53 and dnmt1, the guardians of the genome: implications for acne vulgaris and prostate cancer

HIGHLIGHTS

  • who: Bodo C. Melnik from the (UNIVERSITY) have published the research work: Milk disrupts p53 and DNMT1, the guardians of the genome: implications for acne vulgaris and prostate cancer, in the Journal: (JOURNAL)

SUMMARY

    Or inhibits gene_expression. Intriguingly, several miRNAs detected in human and bovine milk are known suppressors of TP53, the gene expressing p53. The very high sequence homology of human and bovine milk miRNAs, especially in their seed region governing their function, suggests that uptake of milk-derived miRNAs may compromise the delicate balance in the level of key gene regulatory . . .

     

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