Mineralocorticoid receptor antagonists mitigate mitral regurgitation-induced myocardial dysfunction

HIGHLIGHTS

• who: Wei-Ting Chang et al. from the Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan have published the article: Mineralocorticoid Receptor Antagonists Mitigate Mitral Regurgitation-Induced Myocardial Dysfunction, in the Journal: Cells 2022, 11, x FOR PEER REVIEW of /2022/
• what: The authors investigate the efficacy of spironolactone in improving cardiac remodeling in MR-induced HF compared with that of a loop diuretic furosemide.
• how: In the study both clinical observation and a novel mini-invasive rat model of degenerative MR were used to investigate the efficacy . . .
  

   

  

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