Mir-125b downregulates macrophage scavenger receptor type b1 and reverse cholesterol transport

HIGHLIGHTS

  • who: Miguel Hueso from the Department of Nephrology, Hospital Universitari Bellvitge and Bellvitge Research Institute (IDIBELL), L′ Hospitalet de Llobregat, Barcelona, Spain have published the research: MiR-125b downregulates macrophage scavenger receptor type B1 and reverse cholesterol transport, in the Journal: (JOURNAL)
  • what: Since SR-B1 is highly expressed in foam cells within human aortic ATH , here, the authors aimed to evaluate the role of miR-125b in regulating SR-B1-mediated macrophage as well as VSMCs cholesterol efflux to HDL particles in_vitro and the entire macrophage-specific reverse cholesterol transport (RCT) pathway in_vivo. considering . . .

     

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