Mir-132-3p and klf7 as novel regulators of aortic stiffening-associated endmt in type 2 diabetes mellitus

HIGHLIGHTS

• who: Melanie S. Hulshoff from the (UNIVERSITY) have published the research: miR-132-3p and KLF7 as novel regulators of aortic stiffening-associated EndMT in type 2 diabetes mellitus, in the Journal: (JOURNAL)
• what: The authors demonstrate robust CD31/u03b1-SMA and CD31/S100A4 co-localization in aortic sections of db/db mice which was almost absent in control mice. The authors demonstrate a significant upregulation of EndMT transcription factors in aortic sections of db/db mice and diabetic patients. underlying regulator the authors identified miR-132-3p the most significantly downregulated miR in the . . .
  

   

  

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