Mir-150-5p and xist interaction controls monocyte adherence: implications for osteoarthritis therapy

HIGHLIGHTS

  • who: Yu-Han Wang from the National Ilan University, Taiwan have published the research work: miR-150-5p and XIST interaction controls monocyte adherence: Implications for osteoarthritis therapy, in the Journal: (JOURNAL)
  • what: The authors analyzed the RNA-seq platform GSE143514 and used ENCORI and miRWalk2.0 miRNA prediction software to select and showed that miR-150-5p significantly reduced VCAM-1 and CD11b expression . The authors demonstrate that upregulation of miR-1505p interferes with XIST regulation and thereby enhances VCAM-1dependent monocyte adherence to OASFs .
  • future: Whether miR-150-5p regulates lymphocyte . . .

     

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