Mir-181a-5p inhibits pyroptosis in sepsis-induced acute kidney injury through downregulation of nek7

HIGHLIGHTS

  • who: Meng Zhang and colleagues from the Department of Critical Care Medicine, Beijing Friendship Hospital, Capital Medical University, No, Yong'an Road, Xicheng District, Beijing, China have published the Article: miR-181a-5p Inhibits Pyroptosis in Sepsis-Induced Acute Kidney Injury through Downregulation of NEK7, in the Journal: Journal of Immunology Research of 10/08/2022
  • what: The study provides a new potential therapeutic target for S-AKI therapy.
  • how: The results indicated that pyroptosis of HK-2 cells could activate both canonical and noncanonical inflammasomes. The results showed that miRNA-181a-5p . . .

     

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