Mir-200c downregulates hif-1α and inhibits migration of lung cancer cells

HIGHLIGHTS

• who: Yuree Byun from the Graduate School of Biotechnology, Kyung Hee University, Yongin, Republic of Korea have published the article: MiR-200c downregulates HIF-1α and inhibits migration of lung cancer cells, in the Journal: (JOURNAL)
• what: In this study miRNAs targeting HIF-1α were identified and their effects on its expression and downstream target genes under hypoxic conditions were investigated. The authors show that HIF-1α, a key regulator of hypoxia signaling, is negatively regulated by miR-200c in lung carcinoma cells. Since the finding that miR-200c regulates HIF-1α expression is an . . .
  

   

  

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