Mir-214-3p deficiency enhances caspase-1-dependent pyroptosis of microglia in white matter injury

HIGHLIGHTS

  • who: Liufang He et al. from the Department of Neonatology, Affiliated Longhua People's Hospital, Southern Medical University (Longhua People's Hospital), Shenzhen, Guangdong, China have published the Article: miR-214-3p Deficiency Enhances Caspase-1-Dependent Pyroptosis of Microglia in White Matter Injury, in the Journal: Journal of Immunology Research of 22/08/2022
  • what: The authors report that the caspase-1 inflammasome is abundantly activated in the microglia of WMI mice and results in increased pyroptosis of microglia. Together, this study reported that via suppressing the transcription of NEK7, miR-214-3p reduced . . .

     

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