Mir-29b suppresses tumor growth and metastasis in colorectal cancer via downregulating tiam1 expression and inhibiting epithelial–mesenchymal transition

HIGHLIGHTS

  • who: B Wang from the DepartmentMedical University, Guangzhou, China have published the research: miR-29b suppresses tumor growth and metastasis in colorectal cancer via downregulating Tiam1 expression and inhibiting epithelial–mesenchymal transition, in the Journal: (JOURNAL)
  • what: This study provides novel basis for the abnormal expression of Tiam1 in CRC.
  • how: Because proteomic studies revealed miR-29b to be involved in signaling transduction pathways the authors carried out a western blot analysis of the phosphorylation status of proteins involved in EMT signaling. Data were analyzed using SPSS version 13.0 software (SPSS Chicago . . .

     

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