Mir-302a/twf1 axis impairs the myogenic differentiation of progenitor cells through f-actin-mediated yap1 activation

HIGHLIGHTS

  • who: Mai Thi Nguyen and Wan Lee from the Department of Biochemistry, Dongguk University College of Medicine, Dongdae-ro, Gyeongju, Republic of Korea have published the Article: Mir-302a/TWF1 Axis Impairs the Myogenic Differentiation of Progenitor Cells through F-Actin-Mediated YAP1 Activation, in the Journal: (JOURNAL)
  • what: This study demonstrated that SFA-inducible miR-302a suppresses TWF1 expression epigenetically and impairs myogenic differentiation by facilitating myoblast proliferation via F-actin-mediated activation. In accordance with the previous findings , this study shows that TWF1 knockdown by siTWF1 stimulated the nuclear translocation of YAP1 and . . .

     

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