Mir-409-3p represses cited2 to refine neocortical layer v projection neuron identity

HIGHLIGHTS

• who: Jessica L. MacDonald and Suzanne Tharin from the Duke University, United States have published the Article: miR-409-3p represses Cited2 to refine neocortical layer V projection neuron identity, in the Journal: (JOURNAL)
• what: The authors investigate whether CITED2 is also necessary for the establishment of layer V callosal projection neurons, and whether it is repressed by members of the evolutionarily acquired Mirg/12qF1 miRNA cluster to refine the identity of layer V corticospinal projection neurons. The authors show that miR-4093p also targets the callosal-expressed, and Lmo4-interacting, transcriptional regulator Cited2 in . . .
  

   

  

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