Mir-4721, induced by ebv-mir-bart22, targets gsk3β to enhance the tumorigenic capacity of npc through the wnt/β-catenin pathway

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  • who: ZiBo Tang from the Center, Integrated Hospital of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China have published the article: miR-4721, Induced by EBV-miR-BART22, Targets GSK3β to Enhance the Tumorigenic Capacity of NPC through the WNT/β-catenin Pathway, in the Journal: (JOURNAL) of 10/05/2020
  • what: The study shows that miR-4721, as an oncogenic (onco-)miRNA, is involved in the EBV-miR-BART22 regulatory mechanism through a PI3K/AKT/c-JUN/Sp1 signaling axis to enhance the tumorigenic capacity by activating the WNT/b-catenin pathway.
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