Mir-cabiner: a universal microrna sensing platform based on self-stacking cascaded bicyclic dna circuit-mediated crispr/cas12a

HIGHLIGHTS

  • What: The results demonstrated the realization of precise detection of individual miRNAs and the universal detection of different miRNA.
  • Who: ruijia deng from the Department of Clinical Laboratory Medicine Third Military Medical University (Army Medical University) , Gaotanyan, Shapingba District, Chongqing, China have published the research: miR-Cabiner: A universal microRNA sensing platform based on self-stacking cascaded bicyclic DNA circuit-mediated CRISPR/Cas12a, in the Journal: (JOURNAL)
  • How: To normalize the fluorescence intensity of different concentration of miRNA the slope of fluorescence intensity was used to calculated the detection range and limit of . . .

     

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