Misfolded protein oligomers induce an increase of intracellular ca2+ causing an escalation of reactive oxidative species

HIGHLIGHTS

• who: Giulia Fani from the Department of Experimental and Clinical Biomedical Sciences, Section of Biochemistry, University of Florence, Viale Morgagni, Florence, Italy have published the Article: Misfolded protein oligomers induce an increase of intracellular Ca2+ causing an escalation of reactive oxidative species, in the Journal: (JOURNAL)
• what: Vicious cycles, or positive feedback loops, exist between u00adCa2+ signalling and ROS production [28, 37], and even between Au03b2 production and u00adC a 2+ signalling [55] and between Au03b2 production and ROS production [55], where the various events sustain each other.

SUMMARY

The elevation . . .

 



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