Mismatch repair, p53, and l1 cell adhesion molecule status influence the response to chemotherapy in advanced and recurrent endometrial cancer

HIGHLIGHTS

  • What: This study examined the prognosis of patients with advanced and recurrent EC who received chemotherapy as adjuvant or palliative therapy by investigating progression-free survival (PFS) and overall survival (OS) to determine whether L1CAM can be a useful prognostic marker for these patients. The research team verified the loss of MSH2 or MSH6 and aberrant p53 expression using cervical swab-based gDNA and confirmed its value as a tool that can be used to layer ProMisE molecular classification based on tests and stratification.
  • Who: Jung Chul Kim from the This retrospective cohort study was . . .

     

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