HIGHLIGHTS
- who: Yi Tu and collaborators from the Wuhan, Wuhan, China, Key Laboratory of Growth Regulation and Translational have published the research work: MITA oligomerization upon viral infection is dependent on its N-glycosylation mediated by DDOST, in the Journal: (JOURNAL) of April/21,/2022
- what: The authors report that MITA undergoes DDOST-mediated N-glycosylation in the endoplasmic reticulum (ER) upon DNA viral infection. The authors report that DDOST is an important regulator of the MITA/STING-mediated production of antiviral type I IFNs. The authors reported DDOST as an important regulator that potentiates MITA . . .
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