Mitigates cisplatin-induced lung oxidative stress inflammation and necroptosis by upregulating sirt1

HIGHLIGHTS

  • who: PPARu03b3 and colleagues from the censee MDPI, SwitzerlandDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar University have published the research work: Mitigates Cisplatin-Induced Lung Oxidative Stress Inflammation and Necroptosis by Upregulating SIRT1, in the Journal: Pharmaceuticals 2023, 16, 52. of /2023/
  • what: This study evaluated the effect of the macrolide antibiotic (AZM) on oxidative stress inflammatory response and necroptosis in the lungs of CIS-administered rats pinpointing the involvement of SIRT1 and Nrf2/HO-1 The results of this study provide new information on the protective effect of AZM against CIS . . .

     

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