HIGHLIGHTS
- who: Esmee Vringer from the (UNIVERSITY) have published the article: Mitochondria and cell death-associated inflammation, in the Journal: (JOURNAL) of 29/Nov/2022
- what: The authors discuss how mitochondrial-dependent inflammation may be therapeutically exploited to improve cancer treatment.
- how: The pan-caspase inhibitor Emricasan is known to accumulate in the liver and was tested in clinical trials for NASH and liver transplants with limited beneficial effects .
SUMMARY
Detection of the extracellular mitochondrial metabolite succinate has shown to enhance the immune_response of dendritic cells. mtDNA is one of . . .
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