Mitochondria targeted antioxidant significantly alleviates preeclampsia caused by 11-hsd2 dysfunction via opa1 and mtdna maintenance

HIGHLIGHTS

  • who: Jing Long et al. from the Department of Gynecology and Obstetrics, Xiangya Hospital Central South University have published the article: Mitochondria Targeted Antioxidant Significantly Alleviates Preeclampsia Caused by 11-HSD2 Dysfunction via OPA1 and MtDNA Maintenance, in the Journal: Antioxidants 2022, 1505 of 27/06/2022
  • what: The aim of this study were to elucidate the molecular mechanisms underlying 11u03b2-HSD2 dysfunction-mediated PE features and seek valuable therapeutic targets. The authors intended to further investigate the molecular mechanisms responsible for mitochondrial dysfunction in the placentas of PE-like model. This study has revealed . . .

     

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