Mitochondria-targeted triphenylamine derivatives activatable by two-photon excitation for triggering and imaging cell apoptosis

HIGHLIGHTS

• who: Rahima Chennoufi from the Université universitaire, Orsay, France have published the research work: Mitochondria-targeted Triphenylamine Derivatives Activatable by Two-Photon Excitation for Triggering and Imaging Cell Apoptosis, in the Journal: Scientific Reports Scientific Reports

SUMMARY

Accordingly, when fixed using paraformaldehyde, TPA-treated cells such as MCF7 (breast cancer) or HeLa (cervical cancer) clearly showed a nuclear localization of TPAs with bright staining in two-photon imaging (Fig 1b). Accordingly, the authors previously shown that photoactivation of TPAs led to the cleavage of the nuclear DNA repair enzyme PARP-1 (poly-ADP . . .

 



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