Mitochondrial apoptosis and fak signaling disruption by a novel histone deacetylase inhibitor, htpb, in antitumor and antimetastatic mouse models

HIGHLIGHTS

• who: Mitochondrial Apoptosis and collaborators from the Department of Internal Medicine, Chi Center, Tainan, Taiwan, Department of Pharmacology, Kung University, Tainan, Taiwan, Institute of have published the Article: Mitochondrial Apoptosis and FAK Signaling Disruption by a Novel Histone Deacetylase Inhibitor, HTPB, in Antitumor and Antimetastatic Mouse Models, in the Journal: (JOURNAL) of January/18,/2012
• what: Methodology/Principal Findings: Here the authors propose a novel HDAC inhibitor N-Hydroxy-4-(4-phenylbutyryl-amino) benzamide (HTPB) as a potential chemotherapeutic drug for solid tumors. In the present study, the antitumor and antimetastatic activities of HTPB and . . .
  

   

  

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