Mitochondrial dna mutations provoke dominant inhibition of mitochondrial inner membrane fusion

HIGHLIGHTS

• who: Mitochondrial DNA Mutations Provoke and collaborators from the 095, Bordeaux, FranceEditor: Yidong Bai, University of Texas Health Science Center at San Antonio, United States of America have published the research: Mitochondrial DNA Mutations Provoke Dominant Inhibition of Mitochondrial Inner Membrane Fusion, in the Journal: PLOS ONE | www.plosone.org of November/16,/2012
• what: The authors demonstrate that despite metabolic compensation by glycolysis OXPHOS defects are associated to a selective inhibition of inner but not outer membrane fusion. The authors used fusion assays based on mitochondrial content mixing to investigate mitochondrial fusion in OXPHOSdeficient . . .
  

   

  

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