Mitochondrial dna variants and common diseases: a mathematical model for the diversity of age-related mtdna mutations

HIGHLIGHTS

  • who: Huanzheng Li and colleagues from the Wenzhou Key Laboratory of Birth Defects, Wenzhou Central Hospital, Wenzhou, Zhejiang, China have published the paper: Mitochondrial DNA Variants and Common Diseases: A Mathematical Model for the Diversity of Age-Related mtDNA Mutations, in the Journal: (JOURNAL)
  • what: Instead, for the purposes of this review, the authors will focus primarily on a discussion of mtDNA mutations, how they are acquired, and how they may lead to disease in patients with common disease conditions. The analysis showed a 63% increase in the number of mutations in the noncoding mtDNA . . .

     

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