Mitochondrial dysfunction in heart failure and its therapeutic implications

HIGHLIGHTS

  • who: Xiaogang Guo from the Children`s Hospital, Australia Virginia Commonwealth University have published the Article: Mitochondrial dysfunction in heart failure and its therapeutic implications, in the Journal: (JOURNAL)

SUMMARY

    Replacing fatty_acids by glucose is considered to be able to increase oxygen efficiency and benefit energy provision in failing heart. Amorim et_al reported that insulin-induced phosphorylation of Akt is normal and the expression of glucose transporter type 4 is unchanged, while the expression of the genes regulating fatty_acid oxidation, e_g, long-chain-acyl-coenzyme A dehydrogenase, carnitine palmitoyltransferase 1 (CPT I) and . . .

     

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