Mitochondrial dysfunction in individuals with diabetic kidney disease: a systematic review

HIGHLIGHTS

  • who: Nicole Flemming et al. from the School of Medicine and Dentistry, Griffith University, Birtinya, Australia have published the research: Mitochondrial Dysfunction in Individuals with Diabetic Kidney Disease: A Systematic Review, in the Journal: Cells 2022, 2481 of 30/03/2022
  • what: The aim of this study was to systematically review the evidence for systemic and kidney-specific mitochondrial dysfunction in human DKD, and to determine whether this area requires further research. Four studies reported decreased mitochondrial biogenesis in individuals with DKD, indicating that decreased biogenesis could contribute to decreased mtDNA content and reduced capacity . . .

     

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