HIGHLIGHTS
- who: December et al. from the The University of Iowa, United States have published the paper: Mitochondrial dysfunction in pulmonary arterial hypertension, in the Journal: (JOURNAL)
- what: The aim of this paper is to review mitochondrial metabolic pathways and related mechanisms and summarize current state-of-the-art treatments for PAH. manifestations and treatment at the 2018 World Hypertension Symposium meeting. The contraction of PASMCs caused by hypoxia is the key factor to trigger hypoxic pulmonary vasoconstriction, and the increase of intracellular Ca2+ level is one of the main reasons for the contraction of PASMCs . . .
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